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2017

Tesmar A, Hoffmann M, Pippel J, Fayad A, Dausend-Werner S, Bauer A, Blankenfeldt W, Müller R – Total Biosynthesis of the Pyrrolo[4,2]benzodiazepine Scaffold Tomaymycin on an In Vitro Reconstituted NRPS System, Cell chemical biology 2017
DOI: 10.1016/j.chembiol.2017.08.001
Hüttel S, Testolin G, Herrmann J, Planke T, Gille F, Moreno M, Stadler M, Brönstrup M, Kirschning A, Müller R – Discovery and total synthesis of natural cystobactamid derivatives with superior activity against Gram-negative pathogens, Angew. Chem. Int. Ed. Engl. 2017
Pubmed: 28730677  
DOI: 10.1002/anie.201705913
Trauner D, Cheng B, Müller R – Total syntheses of cystobactamids and structural confirmation of cystobactamid 919-2, Angewandte Chemie (International ed. in English) 2017
Pubmed: 28731542  
DOI: 10.1002/anie.201705387
Kjaerulff L, Raju R, Panter F, Scheid U, Garcia R, Herrmann J, Müller R – Pyxipyrrolones: Structure elucidation and biosynthesis of cytotoxic myxobacterial metabolites, Angewandte Chemie (International ed. in English) 2017, 56, 9614-9618
Pubmed: 28590072  
DOI: 10.1002/anie.201704790
Rox K, Rohde M, Chhatwal G, Müller R – Disorazoles block group A streptococcal invasion into epithelial cells via interference with the host factor ezrin, Cell Chem. Biol. 2017, 24, 159-170
DOI: 10.1016/j.chembiol.2016.12.011
Viehrig K, Surup F, Volz C, Herrmann J, Abou Fayad A, Adam S, Kohnke J, Trauner D, Muller R – Structure and biosynthesis of crocagins: polycyclic postranslationally modified ribosomal peptides from Chondromyces crocatus, Angew. Chem. Int. Ed. Engl. 2017
Pubmed: 28544148  
DOI: 10.1002/anie.201612640
Bock T, Volz C, Hering V, Scrima A, Müller R, Blankenfeldt W – The AibR-isovaleryl coenzyme A regulator and its DNA binding site - a model for the regulation of alternative de novo isovaleryl coenzyme A biosynthesis in Myxococcus xanthus, Nucleic Acids Res. 2017, 45, 2166-2178
Pubmed: 27940564  
DOI: 10.1093/nar/gkw1238
Fu C, Auerbach D, Li Y, Scheid U, Luxenburger E, Garcia R, Irschik H, Müller R – Solving the puzzle of the one-carbon loss in ripostatin biosynthesis, Angew. Chem. Int. Ed. Engl. 2017, 56, 2192-2197
DOI: 10.1002/anie.201609950

2016

Steinmetz H, Li J, Fu C, Zaburannyi N, Kunze B, Harmrolfs K, Schmitt V, Herrmann J, Reichenbach H, Hofle G, Kalesse M, Müller R – Isolation, structure elucidation, and (bio)synthesis of Haprolid, a cell-type-specific myxobacterial cytotoxin, Angew. Chem. Int. Ed. Engl. 2016, 55, 10113-7
Pubmed: 27404448  
DOI: 10.1002/anie.201603288
Wang H, Li Z, Jia R, Hou Y, Yin J, Bian X, Li A, Muller R, Stewart A, Fu J, Zhang Y – RecET direct cloning and Redab recombineering of biosynthetic gene clusters, large operons or single genes for heterologous expression, Nat. Protoc. 2016, 11, 1175-1190
Pubmed: 27254463  
DOI: 10.1038/nprot.2016.054
Zaburannyi N, Bunk B, Maier J, Overmann J, Müller R – Genome analysis of the fruiting body forming myxobacterium Chondromyces crocatus reveals high potential for natural product Biosynthesis, Appl. Environ. Microbiol. 2016, 82, 1945-57
Pubmed: 26773087  
DOI: 10.1128/AEM.03011-15
Lee W, Schaefer K, Qiao Y, Srisuknimit V, Steinmetz H, Müller R, Kahne D, Walker S – The mechanism of action of lysobactin, J. Am. Chem. Soc. 2016, 138, 100-103
Pubmed: 26683668  
DOI: 10.1021/jacs.5b11807
Gemperlein K, Zipf G, Bernauer H, Müller R, Wenzel S – Metabolic engineering of Pseudomonas putida for production of docosahexaenoic acid based on a myxobacterial PUFA synthase , Metab. Eng. 2016, 33, 98-108
Pubmed: 26617065  
DOI: 10.1016/j.ymben.2015.11.001

2015

Wenzel S, Hoffmann H, Zhang J, Debussche L, Haag-Richter S, Kurz M, Nardi F, Lukat P, Kochems I, Tietgen H, Schummer D, Nicolas J, Calvet L, Czepczor V, Vrignaud P, Mühlenweg A, Pelzer S, Müller R, Brönstrup M – Production of the bengamide class of marine natural products in myxobacteria: biosynthesis and structure-activity relationships, Angew. Chem. Int. Ed. Engl. 2015, 54, 15560-4
Pubmed: 26514647  
DOI: 10.1002/anie.201508277
Mohr K, Volz C, Jansen R, Wray V, Hoffmann J, Bernecker S, Wink J, Gerth K, Stadler M, Müller R – Pinensins: the first antifungal lantibiotics, Angew. Chem. Int. Ed. Engl. 2015, 127, 11254-11258
Pubmed: 26211520  
DOI: 10.1002/anie.201500927
Keller L, Plaza A, Dubiella C, Groll M, Kaiser M, Muller R – Macyranones: Structure, Biosynthesis, and Binding Mode of an Unprecedented Epoxyketone that Targets the 20S Proteasome, J. Am. Chem. Soc. 2015, 137, 8121-30
Pubmed: 26050527  
DOI: 10.1021/jacs.5b03833
Fu C, Keller L, Bauer A, Brönstrup M, Froidbise A, Hammann P, Herrmann J, Mondesert G, Kurz M, Schiell M, Schummer D, Toti L, Wink J, Müller R – Biosynthetic studies of telomycin reveal new lipopeptides with enhanced activity, J. Am. Chem. Soc. 2015, 137, 7692-7705
Pubmed: 26043159  
DOI: 10.1021/jacs.5b01794
Kling A, Lukat P, Almeida D, Bauer A, Fontaine E, Sordello S, Zaburannyi N, Herrmann J, Wenzel S, König C, Ammerman N, Barrio M, Borchers K, Bordon-Pallier F, Brönstrup M, Courtemanche G, Gerlitz M, Geslin M, Hammann P, Heinz D, Hoffmann H, Klieber S, Kohlmann M, Kurz M, Lair C, Matter H, Nuermberger E, Tyagi S, Fraisse L, Grosset J, Lagrange S, Müller R – Targeting DnaN for tuberculosis therapy using novel griselimycins, Science 2015, 348, 1106-1112
Pubmed: 26045430  
DOI: 10.1126/science.aaa4690
Sucipto H, Sahner J, Prusov E, Wenzel S, Hartmann R, Koehnke J, Müller R – In Vitro reconstitution of α-Pyrone ring formation in myxopyronin biosynthesis, Chem. Sci. 2015, 6, 5076-5085
DOI: 10.1039/C5SC01013F
Bian X, Plaza A, Zhang Y, Müller R – Two more pieces of the colibactin genotoxin puzzle from Escherichia coli show incorporation of an unusual 1-aminocyclopropanecarboxylic acid moiety, Chem. Sci. 2015, 6, 3154-3160
DOI: 10.1039/c5sc00101c

2014

Berod L, Friedrich C, Nandan A, Freitag J, Hagemann S, Harmrolfs K, Sandouk A, Hesse C, Castro C, Bähre H, Tschirner S, Gorinski N, Gohmert M, Mayer C, Huehn J, Ponimaskin E, Abraham W, Müller R, Lochner M, Sparwasser T – De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells, Nat. Med. 2014, 20, 1327-1333
Pubmed: 25282359  
DOI: 10.1038/nm.3704
Baumann S, Herrmann J, Raju R, Steinmetz H, Mohr K, Hüttel S, Harmrolfs K, Stadler M, Müller R – Cystobactamids: myxobacterial topoisomerase inhibitors exhibiting potent antibacterial activity, Angew. Chem. Int. Ed. Engl. 2014, 53, 14605-14609
Pubmed: 25510965  
DOI: 10.1002/anie.201409964
Hoffmann T, Krug D, Hüttel S, Müller R – Improving natural products identification through targeted LC-MS/MS in an untargeted secondary metabolomics workflow, Anal. Chem. 2014, 86, 10780-10788
Pubmed: 25280058  
DOI: 10.1021/ac502805w
Reker D, Perna A, Rodrigues T, Schneider P, Reutlinger M, Mönch B, Koeberle A, Lamers C, Gabler M, Steinmetz H, Müller R, Schubert-Zsilavecz M, Werz O, Schneider G – Revealing the macromolecular targets of complex natural products, Nat. Chem. 2014, 6, 1072-1078
Pubmed: 25411885  
DOI: 10.1038/nchem.2095
Surup F, Viehrig K, Mohr K, Herrmann J, Jansen R, Müller R – Disciformycins A and B: 12-membered macrolide glycoside antibiotics from the myxobacterium Pyxidicoccus fallax active against multiresistant staphylococci , Angew. Chem. Int. Ed. Engl. 2014, 49, 13588-13591
Pubmed: 25294799  
DOI: 10.1002/anie.201406973
Müller S, Rachid S, Hoffmann T, Surup F, Volz C, Zaburannyi N, Müller R – Biosynthesis of crocacin involves an unusual hydrolytic release domain showing similarity to condensation domains, Chem. Biol. 2014, 21, 855-865
Pubmed: 24981773  
DOI: 10.1016/j.chembiol.2014.05.012
Etzbach L, Plaza A, Garcia R, Baumann S, Müller R – Cystomanamides: structure and biosynthetic pathway of a family of glycosylated lipopeptides from myxobacteria, Org. Lett. 2014, 16, 2414-2417
Pubmed: 24735013  
DOI: 10.1021/ol500779s
Gemperlein K, Rachid S, Garcia R, Wenzel S, Müller R – Polyunsaturated fatty acid biosynthesis in myxobacteria, Chem. Sci. 2014, 5, 1733-1741
DOI: 10.1039/C3SC53163E
Kolinko I, Lohße A, Borg S, Raschdorf R, Jogler C, Tu Q, Pósfai M, Tompa E, Plitzko J, Brachmann A, Wanner G, Müller R, Zhang Y, Schüler D – Biosynthesis of magnetic nanostructures in a foreign organism by transfer of bacterial magnetosome gene clusters, Nat. Nanotechnol. 2014, 9, 193-197
Pubmed: 24561353  
DOI: 10.1038/nnano.2014.13

2013

Hoffmann T, Müller S, Nadmid S, Garcia R, Müller R – Microsclerodermins from terrestrial myxobacteria: An intriguing biosynthesis likely connected to a sponge symbiont, J. Am. Chem. Soc. 2013, 45, 16904-16911
Pubmed: 24124771  
DOI: 10.1021/ja4054509
Viehrig K, Surup F, Harmrolfs K, Jansen R, Kunze B, Müller R – Concerted action of P450 plus helper protein to form the amino-hydroxy-piperidone moiety of the potent protease inhibitor crocapeptin, J. Am. Chem. Soc. 2013, 135, 16885-16894
Pubmed: 24171398  
DOI: 10.1021/ja4047153

2012

Jahns C, Hoffmann T, Müller S, Gerth K, Washausen P, Höfle G, Reichenbach H, Kalesse M, Müller R – Pellasoren: structure elucidation, biosynthesis, and total synthesis of a cytotoxic secondary metabolite from Sorangium cellulosum, Angew. Chem. Int. Ed. Engl. 2012, 51, 5239-5243
Pubmed: 22488911  
DOI: 10.1002/anie.201200327
Fu J, Bian X, Hu S, Wang H, Huang F, Seibert P, Plaza A, Xia L, Müller R, Stewart A, Zhang Y – Full-length RecE enhances linear-linear homologous recombination and facilitates direct cloning for bioprospecting, Nat. Biotechnol. 2012, 30, 440-446
Pubmed: 22544021  
DOI: 10.1038/nbt.2183
Li Y, Luxenburger E, Müller R – An alternative isovaleryl CoA biosynthetic pathway involving a previously unknown 3-methylglutaconyl CoA decarboxylase, Angew. Chem. Int. Ed. Engl. 2012, 52, 1304-1308
Pubmed: 23225771  
DOI: 10.1002/anie.201207984
Volz C, Kegler C, Müller R – Enhancer binding proteins act as hetero-oligomers and link secondary metabolite production to myxococcal development, motility and predation, Chem. Biol. 2012, 19, 1447-1459
Pubmed: 23177199  
DOI: 10.1016/j.chembiol.2012.09.010
Huo L, Rachid S, Stadler M, Wenzel S, Müller R – Synthetic biotechnology to study and engineer ribosomal bottromycin biosynthesis, Chem. Biol. 2012, 19, 1278-1287
Pubmed: 23021914  
DOI: 10.1016/j.chembiol.2012.08.013
Katsuyama Y, Harmrolfs K, Pistorius D, Li Y, Müller R – A semipinacol rearrangement directed by an enzymatic system featuring dual-function FAD-dependent monooxygenase, Angew. Chem. Int. Ed. Engl. 2012, 51, 9437-9440
Pubmed: 22907798  
DOI: 10.1002/anie.201204138
Barbier J, Jansen R, Irschik H, Benson S, Gerth K, Böhlendorf B, Höfle G, Reichenbach H, Wegner J, Zeilinger C, Kirschning A, Müller R – Isolation and total synthesis of icumazoles and noricumazoles--antifungal antibiotics and cation-channel blockers from Sorangium cellulosum, Angew. Chem. Int. Ed. Engl. 2012, 51, 1256-1260
Pubmed: 22213143  
DOI: 10.1002/anie.201106435
Cortina N, Krug D, Plaza A, Revermann O, Müller R – Myxoprincomide: a natural product from Myxococcus xanthus discovered by comprehensive analysis of the secondary metabolome, Angew. Chem. Int. Ed. Engl. 2012, 51, 811-816
Pubmed: 22162209  
DOI: 10.1002/anie.201106305
Quade N, Huo L, Rachid S, Heinz D, Müller R – Unusual carbon fixation gives rise to diverse polyketide extender units, Nat. Chem. Biol. 2012, 8, 117-124
Pubmed: 22138621  
DOI: 10.1038/nchembio.734

2011

Pistorius D, Li Y, Mann S, Müller R – Unprecedented anthranilate priming involving two enzymes of the acyl adenylating superfamily in aurachin biosynthesis, J. Am. Chem. Soc. 2011, 133, 12362-12365
Pubmed: 21770425  
DOI: 10.1021/ja203653w
Dehn R, Katsuyama Y, Weber A, Gerth K, Jansen R, Steinmetz H, Höfle G, Müller R, Kirschning A – Molecular basis of elansolid biosynthesis: evidence for an unprecedented quinone methide initiated intramolecular Diels-Alder cycloaddition/macrolactonization, Angew. Chem. Int. Ed. Engl. 2011, 50, 3882-3887
Pubmed: 21472917  
DOI: 10.1002/anie.201006880
Steinmetz H, Gerth K, Jansen R, Schläger N, Dehn R, Reinecke S, Kirschning A, Müller R – Elansolid A, a unique macrolide antibiotic from Chitinophaga sancti isolated as two stable atropisomers, Angew. Chem. Int. Ed. Engl. 2011, 50, 532-536
Pubmed: 21154488  
DOI: 10.1002/anie.201005226

2010

Binz T, Maffioli S, Sosio M, Donadio S, Müller R – Insights into an unusual nonribosomal peptide synthetase biosynthesis: identification and characterization of the GE81112 biosynthetic gene cluster, J. Biol. Chem. 2010, 285, 32710-32719
Pubmed: 20710026  
DOI: 10.1074/jbc.M110.146803
Buntin K, Irschik H, Weissman K, Luxenburger E, Blöcker H, Müller R – Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity, Chem. Biol. 2010, 17, 342-356
Pubmed: 20416506  
DOI: 10.1016/j.chembiol.2010.02.013
Chai Y, Pistorius D, Ullrich A, Weissman K, Kazmaier U, Müller R – Discovery of 23 natural tubulysins from Angiococcus disciformis An d48 and Cystobacter SBCb004, Chem. Biol. 2010, 17, 296-309
Pubmed: 20338521  
DOI: 10.1016/j.chembiol.2010.01.016
Rachid S, Revermann O, Dauth C, Müller R – Characterization of a novel type of oxidative decarboxylase involved in the biosynthesis of the styryl moiety of chondrochloren from an acylated tyrosine, J. Biol. Chem. 2010, 285, 12482-12489
Pubmed: 20080978  
DOI: 10.1074/jbc.M109.079707

2009

Wenzel S, Müller R – The impact of genomics on the exploitation of the myxobacterial secondary metabolome, Nat. Prod. Rep. 2009, 26, 1385-1407
Pubmed: 19844638  
DOI: 10.1039/b817073h
Rachid S, Scharfe M, Blöcker H, Weissman K, Müller R – Unusual chemistry in the biosynthesis of the antibiotic chondrochlorens, Chem. Biol. 2009, 16, 70-81
Pubmed: 19171307  
DOI: 10.1016/j.chembiol.2008.11.005

2008

Menche D, Arikan F, Perlova O, Horstmann N, Ahlbrecht W, Wenzel S, Jansen R, Irschik H, Müller R – Stereochemical determination and complex biosynthetic assembly of etnangien, a highly potent RNA polymerase inhibitor from the myxobacterium Sorangium cellulosum , J. Am. Chem. Soc. 2008, 130, 14234-14243
Pubmed: 18826315  
DOI: 10.1021/ja804194c
Meiser P, Weissman K, Bode H, Krug D, Dickschat J, Sandmann A, Müller R – DKxanthene biosynthesis - understanding the basis for diversity-oriented synthesis in myxobacterial secondary metabolism, Chem. Biol. 2008, 15, 771-781
Pubmed: 18721748  
DOI: 10.1016/j.chembiol.2008.06.005
Perez J, Castaneda-Garcia A, Jenke-Kodama H, Müller R, Munoz-Dorado J – Eukaryotic-like protein kinases in the prokaryotes and the myxobacterial kinome, Proc. Natl. Acad. Sci. USA 2008, 105, 15950-15955
Pubmed: 18836084  
DOI: 10.1073/pnas.0806851105
Li Y, Weissman K, Müller R – Myxochelin biosynthesis: direct evidence for two- and four-electron reduction of a carrier protein-bound thioester, J. Am. Chem. Soc. 2008, 130, 7554-7555
Pubmed: 18498160  
DOI: 10.1021/ja8025278
Buntin K, Rachid S, Scharfe M, Blöcker H, Weissman K, Müller R – Production of the antifungal isochromanone ajudazols A and B in Chondromyces crocatus Cm c5: biosynthetic machinery and cytochrome P450 modifications , Angew. Chem. Int. Ed. Engl. 2008, 47, 4595-4599
Pubmed: 18461592  
DOI: 10.1002/anie.200705569

2007

Rachid S, Krug D, Weissman K, Muller R – Biosynthesis of (R)-beta-tyrosine and its incorporation into the highly cytotoxic chondramides produced by Chondromyces crocatus, The Journal of biological chemistry 2007, 282, 21810-21817
Pubmed: 17545150  
DOI: 10.1074/jbc.M703439200
Wenzel S, Müller R – Myxobacterial natural product assembly lines: fascinating examples of curious biochemistry, Nat. Prod. Rep. 2007, 24, 1211-1224
Pubmed: 18033576  
DOI: 10.1039/b706416k
Rachid S, Gerth K, Kochems I, Müller R – Deciphering regulatory mechanisms for secondary metabolite production in the myxobacterium Sorangium cellulosum So ce56 , Mol. Microbiol. 2007, 63, 1783-1796
Pubmed: 17367395  
DOI: 10.1111/j.1365-2958.2007.05627.x
Sandmann A, Dickschat J, Jenke-Kodama H, Kunze B, Dittmann E, Müller R – A type II polyketide synthase from the gram-negative bacterium Stigmatella aurantiaca is involved in aurachin alkaloid biosynthesis , Angew. Chem. Int. Ed. Engl. 2007, 46, 2712-2716
Pubmed: 17335090  
DOI: 10.1002/anie.200603513

2006

Meiser P, Bode H, Müller R – The unique DKxanthene secondary metabolite family from the myxobacterium Myxococcus xanthus is required for developmental sporulation, Proc. Natl. Acad. Sci. U.S.A. 2006, 103, 19128-19133
Pubmed: 17148609  
DOI: 10.1073/pnas.0606039103
Wenzel S, Williamson R, Grünanger C, Xu J, Gerth K, Martinez R, Moss S, Carroll B, Grond S, Unkefer C, Müller R, Floss H – On the biosynthetic origin of methoxymalonyl-acyl carrier protein, the substrate for incorporation of "glycolate" units into ansamitocin and soraphen A, J. Am. Chem. Soc. 2006, 128, 14325-14336
Pubmed: 17076505  
DOI: 10.1021/ja064408t
Wenzel S, Meiser P, Binz T, Mahmud T, Müller R – Nonribosomal Peptide Biosynthesis: Point Mutations and Module Skipping Lead to Chemical Diversity, Angew. Chem. Int. Ed. Engl. 2006, 45, 2296-2301
Pubmed: 16506259  
DOI: 10.1002/anie.200503737

2005

Bode H, Müller R – The impact of bacterial genomics on natural product research, Angew. Chem. Int. Ed. Engl. 2005, 44, 6828-6846
Pubmed: 16249991  
DOI: 10.1002/anie.200501080
Wenzel S, Gross F, Zhang Y, Fu J, Stewart F, Müller R – Heterologous expression of a myxobacterial natural products assembly line in pseudomonads via red/ET recombineering, Chem. Biol. 2005, 12, 349-356
Pubmed: 15797219  
DOI: 10.1016/j.chembiol.2004.12.012
Bode H, Dickschat J, Kroppenstedt R, Schulz S, Müller R – Biosynthesis of iso-fatty acids in myxobacteria: iso-even fatty acids are derived from Ó-aoxidation of iso-odd fatty acids, J. Am. Chem. Soc. 2005, 127, 532-533
Pubmed: 15643871  
DOI: 10.1021/ja043570y

2004

Sandmann A, Sasse F, Müller R – Identification and analysis of the core biosynthetic machinery of tubulysin, a potent cytotoxin with potential anticancer activity, Chem. Biol. 2004, 11, 1071-1079
Pubmed: 15324808  
DOI: 10.1016/j.chembiol.2004.05.014
Bode H, Wenzel S, Irschik H, Höfle G, Müller R – Unusual biosynthesis of leupyrrins in the myxobacterium Sorangium cellulosum , Angew. Chem. Int. Ed. Engl. 2004, 43, 4163-4167
Pubmed: 15307077  
DOI: 10.1002/anie.200454240

2003

Weinig S, Hecht H, Mahmud T, Müller R – Melithiazol biosynthesis: further insights into myxobacterial PKS/NRPS systems and evidence for a new subclass of methyl transferases, Chem. Biol. 2003, 10, 939-952
Pubmed: 14583260  
DOI: 10.1016/j.chembiol.2003.09.012
Weinig S, Mahmud T, Müller R – Markerless mutations in the myxothiazol biosynthetic gene cluster: A delicate megasynthetase with a superfluous nonribosomal peptide synthetase domain, Chem. Biol. 2003, 10, 953-960
Pubmed: 14583261  
DOI: 10.1016/j.chembiol.2003.09.013
Bode H, Zeggel B, Silakowski B, Wenzel S, Reichenbach H, Müller R – Steroid biosynthesis in prokaryotes: identification of myxobacterial steroids and cloning of the first bacterial 2,3(S)-oxidosqualene cyclase from the myxobacterium Stigmatella aurantiaca, Mol. Microbiol. 2003, 47, 471-481
Pubmed: 12519197  
DOI: 10.1046/j.1365-2958.2003.03309.x

2002

Mahmud T, Bode H, Silakowski B, Kroppenstedt R, Xu M, Nordhoff S, Höfle G, Müller R – A novel biosynthetic pathway providing precursors for fatty acid biosynthesis and secondary metabolite formation in myxobacteria, J. Biol. Chem. 2002, 277, 32768-74
Pubmed: 12084727  
DOI: 10.1074/jbc.M205222200
Gaitatzis N, Silakowski B, Kunze B, Nordsiek G, Blöcker H, Höfle G, Müller R – The biosynthesis of the aromatic myxobacterial electron transport inhibitor stigmatellin is directed by a novel type of modular polyketide synthase, J. Biol. Chem. 2002, 277, 13082-13090
Pubmed: 11809757  
DOI: 10.1074/jbc.M111738200

2001

Gaitatzis N, Kunze B, Müller R – In vitro reconstitution of the myxochelin biosynthetic machinery of Stigmatella aurantiaca Sg a15: Biochemical characterization of a reductive release mechanism from nonribosomal peptide synthetases, Proc. Natl. Acad. Sci. USA 2001, 98, 11136-11141
Pubmed: 11562468  
DOI: 10.1073/pnas.201167098
Silakowski B, Nordsiek G, Kunze B, Blöcker H, Müller R – Novel features in a combined polyketide synthase/non-ribosomal peptide synthetase: the myxalamid biosynthetic gene cluster of the myxobacterium Stigmatella aurantiaca Sga15, Chem. Biol. 2001, 8, 59-69
Pubmed: 11182319  
DOI: 10.1016/S1074-5521(00)00056-9

1999

Silakowski B, Schairer H, Ehret H, Kunze B, Weinig S, Nordsiek G, Brandt P, Blöcker H, Höfle G, Beyer S, Müller R – New lessons for combinatorial biosynthesis from myxobacteria. The myxothiazol biosynthetic gene cluster of Stigmatella aurantiaca DW4/3-1, J. Biol. Chem. 1999, 274, 37391-37399
Pubmed: 10601310  
DOI: 10.1074/jbc.274.52.37391

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